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Glutathione peroxidase-1 modulates lipopolysaccharide-induced adhesion molecule expression in endothelial cells by altering CD14 expression

CD14 contributes to LPS signaling in leukocytes through formation of toll-like receptor 4/CD14 receptor complexes; however, a specific role for endogenous cell-surface CD14 in endothelial cells is unclear. We have found that suppression of glutathione peroxidase-1 (GPx-1) in human microvascular endo...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Lubos, Edith, Mahoney, Christopher E., Leopold, Jane A., Zhang, Ying-Yi, Loscalzo, Joseph, Handy, Diane E.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Federation of American Societies for Experimental Biology 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2887263/
https://ncbi.nlm.nih.gov/pubmed/20219985
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.09-147421
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