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Glutathione Peroxidase-3 Deficiency Promotes Platelet-dependent Thrombosis in vivo

BACKGROUND: Glutathione peroxidase-3 (GPx-3) is a selenocysteine-containing plasma protein that scavenges reactive oxygen species in the extracellular compartment. A deficiency of this enzyme has been associated with platelet-dependent thrombosis, and a promoter haplotype with reduced function has b...

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Detalhes bibliográficos
Main Authors: Jin, Richard C., Mahoney, Christopher E., Anderson, Laura (Coleman), Ottaviano, Filomena, Croce, Kevin, Leopold, Jane A., Zhang, Yingyi, Tang, Shiow-Shih, Handy, Diane E., Loscalzo, Joseph
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3107543/
https://ncbi.nlm.nih.gov/pubmed/21518981
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCULATIONAHA.110.000034
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