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Phospholipids enhance nucleation but not elongation of apolipoprotein C-II amyloid fibrils
Amyloid fibrils and their oligomeric intermediates accumulate in several age-related diseases where their presence is considered to play an active role in disease progression. A common characteristic of amyloid fibril formation is an initial lag phase indicative of a nucleation-elongation mechanism...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2010
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2887044/ https://ncbi.nlm.nih.gov/pubmed/20433849 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2010.04.042 |
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