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Fluorescence Detection of a Lipid-induced Tetrameric Intermediate in Amyloid Fibril Formation by Apolipoprotein C-II

The misfolding and self-assembly of proteins into amyloid fibrils that occurs in several debilitating and age-related diseases is affected by common components of amyloid deposits, notably lipids and lipid complexes. We have examined the effect of the short-chain phospholipids, dihexanoylphosphatidy...

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Detalhes bibliográficos
Main Authors: Ryan, Timothy M., Howlett, Geoffrey J., Bailey, Michael F.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3259869/
https://ncbi.nlm.nih.gov/pubmed/18852267
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M804004200
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