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Effect of Apolipoprotein E on Biomarkers of Amyloid Load and Neuronal Pathology in Alzheimer Disease

OBJECTIVE: To study the effect of apolipoprotein E ε4 status on biomarkers of neurodegeneration (atrophy on magnetic resonance imaging [MRI]), neuronal injury (cerebrospinal fluid [CSF] t-tau), and brain Aβ amyloid load (CSF Aβ(1–42)) in cognitively normal subjects (CN), amnestic subjects with mild...

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書誌詳細
主要な著者: Vemuri, Prashanthi, Wiste, Heather J., Weigand, Stephen D., Knopman, David S., Shaw, Leslie M., Trojanowski, John Q., Aisen, Paul S., Weiner, Michael, Petersen, Ronald C., Jack, Clifford R.
フォーマット: Artigo
言語:Inglês
出版事項: 2010
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2886799/
https://ncbi.nlm.nih.gov/pubmed/20373342
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ana.21953
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