Transforming CSF Aβ42 measures into calculated Pittsburgh Compound B (PIBcalc) units of brain Aβ amyloid

BACKGROUND: PIB PET and CSF Aβ42 demonstrate a highly significant inverse correlation. Both are presumed to measure brain Aβ amyloid load. Our objectives were to develop a method to transform CSF Aβ42 measures into calculated PIB measures (PIBcalc) of Aβ amyloid load, and to partially validate the m...

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Autori principali: Weigand, Stephen D., Vemuri, Prashanthi, Wiste, Heather J., Senjem, Matthew L., Pankratz, Vernon S., Aisen, Paul S., Weiner, Michael W., Petersen, Ronald C., Shaw, Leslie M., Trojanowski, John Q., Knopman, David S., Jack, Clifford R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2011
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3060961/
https://ncbi.nlm.nih.gov/pubmed/21282074
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jalz.2010.08.230
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