Hypothetical model of dynamic biomarkers of the Alzheimer’s pathological cascade

Currently available evidence strongly supports the position that the initiating event in Alzheimer’s disease (AD) is related to abnormal processing of β-amyloid (Aβ) peptide, ultimately leading to formation of Aβ plaques in the brain. This process occurs while individuals are still cognitively norma...

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Bibliographic Details
Main Authors: Jack, Clifford R, Knopman, David S, Jagust, William J, Shaw, Leslie M, Aisen, Paul S, Weiner, Michael W, Petersen, Ronald C, Trojanowski, John Q
Format: Artigo
Language:Inglês
Published: 2010
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2819840/
https://ncbi.nlm.nih.gov/pubmed/20083042
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/S1474-4422(09)70299-6
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