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Hypothetical model of dynamic biomarkers of the Alzheimer’s pathological cascade

Currently available evidence strongly supports the position that the initiating event in Alzheimer’s disease (AD) is related to abnormal processing of β-amyloid (Aβ) peptide, ultimately leading to formation of Aβ plaques in the brain. This process occurs while individuals are still cognitively norma...

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Détails bibliographiques
Auteurs principaux: Jack, Clifford R, Knopman, David S, Jagust, William J, Shaw, Leslie M, Aisen, Paul S, Weiner, Michael W, Petersen, Ronald C, Trojanowski, John Q
Format: Artigo
Langue:Inglês
Publié: 2010
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2819840/
https://ncbi.nlm.nih.gov/pubmed/20083042
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/S1474-4422(09)70299-6
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