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Hypothetical model of dynamic biomarkers of the Alzheimer’s pathological cascade

Currently available evidence strongly supports the position that the initiating event in Alzheimer’s disease (AD) is related to abnormal processing of β-amyloid (Aβ) peptide, ultimately leading to formation of Aβ plaques in the brain. This process occurs while individuals are still cognitively norma...

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Библиографические подробности
Главные авторы: Jack, Clifford R, Knopman, David S, Jagust, William J, Shaw, Leslie M, Aisen, Paul S, Weiner, Michael W, Petersen, Ronald C, Trojanowski, John Q
Формат: Artigo
Язык:Inglês
Опубликовано: 2010
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2819840/
https://ncbi.nlm.nih.gov/pubmed/20083042
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/S1474-4422(09)70299-6
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