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A novel quantitative explanation for the autonomic modulation of cardiac pacemaker cell automaticity via a dynamic system of sarcolemmal and intracellular proteins

Classical numerical models have attributed the regulation of normal cardiac automaticity in sinoatrial node cells (SANCs) largely to G protein-coupled receptor (GPCR) modulation of sarcolemmal ion currents. More recent experimental evidence, however, has indicated that GPCR modulation of SANCs autom...

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Detalhes bibliográficos
Main Authors: Maltsev, Victor A., Lakatta, Edward G.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2886657/
https://ncbi.nlm.nih.gov/pubmed/20228256
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00783.2009
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