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Role of heat shock factor-1 activation in the doxorubicin-induced heart failure in mice

Treating cancer patients with chemotherapeutics, such as doxorubicin (Dox), cause dilated cardiomyopathy and congestive heart failure because of oxidative stress. On the other hand, heat shock factor-1 (HSF-1), a transcription factor for heat shock proteins (Hsps), is also known to be activated in r...

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Bibliografiska uppgifter
Huvudupphovsmän: Vedam, Kaushik, Nishijima, Yoshinori, Druhan, Lawrence J., Khan, Mahmood, Moldovan, Nicanor I., Zweier, Jay L., Ilangovan, Govindasamy
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Physiological Society 2010
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2886633/
https://ncbi.nlm.nih.gov/pubmed/20363884
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.01047.2009
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