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Properties of WT and mutant hERG K(+) channels expressed in neonatal mouse cardiomyocytes
Mutations in human ether-a-go-go-related gene 1 (hERG) are linked to long QT syndrome type 2 (LQT2). hERG encodes the pore-forming α-subunits that coassemble to form rapidly activating delayed rectifier K(+) current in the heart. LQT2-linked missense mutations have been extensively studied in noncar...
में बचाया:
| मुख्य लेखकों: | , , , , , , , , , |
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| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
American Physiological Society
2010
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2886621/ https://ncbi.nlm.nih.gov/pubmed/20363883 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.01236.2009 |
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