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A role of complexin-lipid interactions in membrane fusion
Complexins and synaptotagmins regulate calcium-dependent exocytosis. A central helix in complexin confers specific binding to the SNARE fusion machinery. An accessory helix in the amino-terminal region inhibits membrane fusion by blocking SNAREpin zippering. We now show that an amphipathic helix in...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2009
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2886508/ https://ncbi.nlm.nih.gov/pubmed/19540234 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.febslet.2009.06.025 |
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