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A role of complexin-lipid interactions in membrane fusion
Complexins and synaptotagmins regulate calcium-dependent exocytosis. A central helix in complexin confers specific binding to the SNARE fusion machinery. An accessory helix in the amino-terminal region inhibits membrane fusion by blocking SNAREpin zippering. We now show that an amphipathic helix in...
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Hoofdauteurs: | , , , |
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Formaat: | Artigo |
Taal: | Inglês |
Gepubliceerd in: |
2009
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Onderwerpen: | |
Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2886508/ https://ncbi.nlm.nih.gov/pubmed/19540234 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.febslet.2009.06.025 |
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