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A role of complexin-lipid interactions in membrane fusion

Complexins and synaptotagmins regulate calcium-dependent exocytosis. A central helix in complexin confers specific binding to the SNARE fusion machinery. An accessory helix in the amino-terminal region inhibits membrane fusion by blocking SNAREpin zippering. We now show that an amphipathic helix in...

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Bibliografische gegevens
Hoofdauteurs: Seiler, Florian, Malsam, Jörg, Krause, Jean Michel, Söllner, Thomas H.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2009
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2886508/
https://ncbi.nlm.nih.gov/pubmed/19540234
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.febslet.2009.06.025
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