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Tubulin polyglutamylation stimulates spastin-mediated microtubule severing

Posttranslational glutamylation of tubulin is present on selected subsets of microtubules in cells. Although the modification is expected to contribute to the spatial and temporal organization of the cytoskeleton, hardly anything is known about its functional relevance. Here we demonstrate that glut...

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Bibliografische gegevens
Hoofdauteurs: Lacroix, Benjamin, van Dijk, Juliette, Gold, Nicholas D., Guizetti, Julien, Aldrian-Herrada, Gudrun, Rogowski, Krzysztof, Gerlich, Daniel W., Janke, Carsten
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: The Rockefeller University Press 2010
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2886356/
https://ncbi.nlm.nih.gov/pubmed/20530212
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201001024
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