Tubulin polyglutamylation stimulates spastin-mediated microtubule severing

Posttranslational glutamylation of tubulin is present on selected subsets of microtubules in cells. Although the modification is expected to contribute to the spatial and temporal organization of the cytoskeleton, hardly anything is known about its functional relevance. Here we demonstrate that glut...

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Bibliographic Details
Main Authors: Lacroix, Benjamin, van Dijk, Juliette, Gold, Nicholas D., Guizetti, Julien, Aldrian-Herrada, Gudrun, Rogowski, Krzysztof, Gerlich, Daniel W., Janke, Carsten
Format: Artigo
Language:Inglês
Published: The Rockefeller University Press 2010
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Research Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2886356/
https://ncbi.nlm.nih.gov/pubmed/20530212
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201001024
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