Microtubule polyglutamylation and acetylation drive microtubule dynamics critical for platelet formation

BACKGROUND: Upon maturation in the bone marrow, polyploid megakaryocytes elongate very long and thin cytoplasmic branches called proplatelets. Proplatelets enter the sinusoids blood vessels in which platelets are ultimately released. Microtubule dynamics, bundling, sliding, and coiling, drive these...

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Pubblicato in:BMC Biol
Autori principali: van Dijk, Juliette, Bompard, Guillaume, Cau, Julien, Kunishima, Shinji, Rabeharivelo, Gabriel, Mateos-Langerak, Julio, Cazevieille, Chantal, Cavelier, Patricia, Boizet-Bonhoure, Brigitte, Delsert, Claude, Morin, Nathalie
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2018
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6194603/
https://ncbi.nlm.nih.gov/pubmed/30336771
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12915-018-0584-6
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