Tubulin polyglutamylation stimulates spastin-mediated microtubule severing

Posttranslational glutamylation of tubulin is present on selected subsets of microtubules in cells. Although the modification is expected to contribute to the spatial and temporal organization of the cytoskeleton, hardly anything is known about its functional relevance. Here we demonstrate that glut...

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Bibliographische Detailangaben
Hauptverfasser: Lacroix, Benjamin, van Dijk, Juliette, Gold, Nicholas D., Guizetti, Julien, Aldrian-Herrada, Gudrun, Rogowski, Krzysztof, Gerlich, Daniel W., Janke, Carsten
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Rockefeller University Press 2010
Schlagworte:
Research Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2886356/
https://ncbi.nlm.nih.gov/pubmed/20530212
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201001024
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