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The N-terminal 81-aa fragment is critical for UT-A1 urea transporter bioactivity

The serine protease, furin, is involved in the activation of a number of proteins most notably epithelial sodium channels (ENaC). The urea transporter UT-A1, located in the kidney inner medullary collecting duct (IMCD), is important for urine concentrating ability. UT-A1's amino acid sequence h...

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書目詳細資料
Main Authors: Huang, Haidong, Yang, Yuan, Eaton, Douglas C., Sands, Jeff M., Chen, Guangping
格式: Artigo
語言:Inglês
出版: 2010
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2886301/
https://ncbi.nlm.nih.gov/pubmed/20559454
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2174/1875044301003010034
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