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The N-terminal 81-aa fragment is critical for UT-A1 urea transporter bioactivity
The serine protease, furin, is involved in the activation of a number of proteins most notably epithelial sodium channels (ENaC). The urea transporter UT-A1, located in the kidney inner medullary collecting duct (IMCD), is important for urine concentrating ability. UT-A1's amino acid sequence h...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2010
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2886301/ https://ncbi.nlm.nih.gov/pubmed/20559454 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2174/1875044301003010034 |
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