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“Clocks” in the NAD World: NAD as a Metabolic Oscillator for the Regulation of Metabolism and Aging

SIR2 (silent information regulator 2) proteins, now called “sirtuins,” are an evolutionarily conserved family of NAD-dependent protein deacetylases/ADP-ribosyltransferases. Sirtuins have recently attracted major attention in the field of aging research, and it has been demonstrated that SIR2 and its...

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Detalles Bibliográficos
Autor Principal: Imai, Shin-ichiro
Formato: Artigo
Idioma:Inglês
Publicado: 2009
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2886185/
https://ncbi.nlm.nih.gov/pubmed/19897060
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbapap.2009.10.024
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