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A Second Class of Nuclear Receptors for Oxysterols: Regulation of RORα and RORγ activity by 24S-Hydroxycholesterol (Cerebrosterol)

The retinoic acid receptor-related orphan receptor α and γ (RORα [NR1F1] and RORγ [NR1F3]) are members of the nuclear hormone receptor superfamily. These 2 receptors regulate many physiological processes including development, metabolism and immunity. We recently found that certain oxysterols, namel...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Wang, Yongjun, Kumar, Naresh, Crumbley, Christine, Griffin, Patrick R., Burris, Thomas P.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2886165/
https://ncbi.nlm.nih.gov/pubmed/20211758
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbalip.2010.02.012
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