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Towards an understanding of the mechanism of action of praziquantel

Although praziquantel (PZQ) has been used to treat schistosomiasis for over 20 years its mechanism of action remains unknown. We have developed an assay based on the transcriptional response of Schistosoma mansoni PR-1 to heat shock to confirm that while 6-week post-infection (p.i.) schistosomes are...

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書誌詳細
主要な著者: Aragon, Anthony D., Imani, Reza A., Blackburn, Vint R., Cupit, Pauline M., Melman, Sandra D., Goronga, Tinopiwa, Webb, Thomas, Loker, Eric S., Cunningham, Charles
フォーマット: Artigo
言語:Inglês
出版事項: 2008
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2886009/
https://ncbi.nlm.nih.gov/pubmed/19100294
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molbiopara.2008.11.007
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