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Modulation of a Schistosoma mansoni multidrug transporter by the antischistosomal drug praziquantel
P-glycoprotein (Pgp) is an ATP-dependent efflux pump involved in transport of xenobiotics from cells that, when overexpressed, can mediate multidrug resistance in mammalian cells. Pgp may be a candidate target for new anthelmintics, as it plays critical roles in normal cell physiology, in removal of...
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| Autors principals: | , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
The Federation of American Societies for Experimental Biology
2010
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2797036/ https://ncbi.nlm.nih.gov/pubmed/19726755 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.09-137091 |
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