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Deregulation of oncogene-induced senescence and p53 translational control in X-linked dyskeratosis congenita
Defects in ribosome biogenesis and function are present in a growing list of human syndromes associated with cancer susceptibility. One example is X-linked dyskeratosis congenita (X-DC) in which the DKC1 gene, encoding for an enzyme that modifies ribosomal RNA, is found to be mutated. How ribosome d...
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| Auteurs principaux: | , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Nature Publishing Group
2010
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2885924/ https://ncbi.nlm.nih.gov/pubmed/20453831 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2010.83 |
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