Inflammation Anergy in Human Intestinal Macrophages Is Due to Smad-induced IκBα Expression and NF-κB Inactivation

Human intestinal macrophages contribute to tissue homeostasis in noninflamed mucosa through profound down-regulation of pro-inflammatory cytokine release. Here, we show that this down-regulation extends to Toll-like receptor (TLR)-induced cytokine release, as intestinal macrophages expressed TLR3–TL...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Smythies, Lesley E., Shen, Ruizhong, Bimczok, Diane, Novak, Lea, Clements, Ronald H., Eckhoff, Devin E., Bouchard, Phillipe, George, Michael D., Hu, William K., Dandekar, Satya, Smith, Phillip D.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2010
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2885238/
https://ncbi.nlm.nih.gov/pubmed/20388715
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.069955
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados