Dendritic cells transmit HIV-1 through human small intestinal mucosa

To dissect the early events in the transmission of HIV-1 from mother to child, we investigated whether DCs participate in HIV-1 entry into human small intestinal mucosa. We isolated human MNLs from jejunal lamina propria and identified a subpopulation of CD11c(+)HLA-DR(+) MNLs that expressed DC-SIGN...

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Detalhes bibliográficos
Main Authors: Shen, Ruizhong, Smythies, Lesley E., Clements, Ronald H., Novak, Lea, Smith, Phillip D.
Formato: Artigo
Idioma:Inglês
Publicado em: The Society for Leukocyte Biology 2010
Assuntos:
Primary Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2858307/
https://ncbi.nlm.nih.gov/pubmed/20007245
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.0909605
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