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O-GlcNAcylation/Phosphorylation Cycling at Ser(10) Controls Both Transcriptional Activity and Stability of Δ-Lactoferrin

Δ-Lactoferrin (ΔLf) is a transcription factor that up-regulates DcpS, Skp1, and Bax genes, provoking cell cycle arrest and apoptosis. It is post-translationally modified either by O-GlcNAc or phosphate, but the effects of the O-GlcNAc/phosphorylation interplay on ΔLf function are not yet understood....

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Библиографические подробности
Главные авторы: Hardivillé, Stéphan, Hoedt, Esthelle, Mariller, Christophe, Benaïssa, Monique, Pierce, Annick
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Biochemistry and Molecular Biology 2010
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2885199/
https://ncbi.nlm.nih.gov/pubmed/20404350
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.080572
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