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O-GlcNAcylation/Phosphorylation Cycling at Ser(10) Controls Both Transcriptional Activity and Stability of Δ-Lactoferrin
Δ-Lactoferrin (ΔLf) is a transcription factor that up-regulates DcpS, Skp1, and Bax genes, provoking cell cycle arrest and apoptosis. It is post-translationally modified either by O-GlcNAc or phosphate, but the effects of the O-GlcNAc/phosphorylation interplay on ΔLf function are not yet understood....
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| Auteurs principaux: | , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
American Society for Biochemistry and Molecular Biology
2010
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2885199/ https://ncbi.nlm.nih.gov/pubmed/20404350 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.080572 |
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