Sustained O-GlcNAcylation reprograms mitochondrial function to regulate energy metabolism

Dysfunctional mitochondria and generation of reactive oxygen species (ROS) promote chronic diseases, which have spurred interest in the molecular mechanisms underlying these conditions. Previously, we have demonstrated that disruption of post-translational modification of proteins with β-linked N-ac...

Full description

Saved in:
Bibliographic Details
Published in:J Biol Chem
Main Authors: Tan, Ee Phie, McGreal, Steven R., Graw, Stefan, Tessman, Robert, Koppel, Scott J., Dhakal, Pramod, Zhang, Zhen, Machacek, Miranda, Zachara, Natasha E., Koestler, Devin C., Peterson, Kenneth R., Thyfault, John P., Swerdlow, Russell H., Krishnamurthy, Partha, DiTacchio, Luciano, Apte, Udayan, Slawson, Chad
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2017
Subjects:
Glycobiology and Extracellular Matrices
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5592672/
https://ncbi.nlm.nih.gov/pubmed/28739801
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.797944
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items