Regulation of Liver Regeneration by Hepatocyte O-GlcNAcylation in MiceSummary

Background & Aims: The liver has a unique capacity to regenerate after injury in a highly orchestrated and regulated manner. Here, we report that O-GlcNAcylation, an intracellular post-translational modification regulated by 2 enzymes, O-GlcNAc transferase (OGT) and O-GlcNAcase (OGA), is a c...

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Detalhes bibliográficos
Main Authors: Dakota R. Robarts, Steven R. McGreal, David S. Umbaugh, Wendena S. Parkes, Manasi Kotulkar, Sarah Abernathy, Norman Lee, Hartmut Jaeschke, Sumedha Gunewardena, Stephen A. Whelan, John A. Hanover, Natasha E. Zachara, Chad Slawson, Udayan Apte
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2022-01-01
Colecção:Cellular and Molecular Gastroenterology and Hepatology
Assuntos:
Cell Death
HNF4alpha
Proliferation
Partial Hepatectomy
Regeneration
Acesso em linha:http://www.sciencedirect.com/science/article/pii/S2352345X22000145
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