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Restoration of the cAMP second messenger pathway enhances cardiac preservation for transplantation in a heterotopic rat model.
Current organ preservation strategies subject graft vasculature to severe hypoxia (PO2 approximately 20 Torr), potentially compromising vascular function and limiting successful transplantation. Previous work has shown that cAMP modulates endothelial cell (EC) antithrombogenicity, barrier function,...
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| 出版年: | J Clin Invest |
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| 主要な著者: | , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Society for Clinical Investigation
1993
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC288503/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8254053/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI116922 |
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