Restoration of the cAMP second messenger pathway enhances cardiac preservation for transplantation in a heterotopic rat model.

Current organ preservation strategies subject graft vasculature to severe hypoxia (PO2 approximately 20 Torr), potentially compromising vascular function and limiting successful transplantation. Previous work has shown that cAMP modulates endothelial cell (EC) antithrombogenicity, barrier function,...

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Autores principales: Pinsky, D, Oz, M, Liao, H, Morris, S, Brett, J, Sciacca, R, Karakurum, M, Van Lookeren Campagne, M, Platt, J, Nowygrod, R
Formato: Artigo
Lenguaje:Inglês
Publicado: 1993
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC288503/
https://ncbi.nlm.nih.gov/pubmed/8254053
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