Restoration of the cAMP second messenger pathway enhances cardiac preservation for transplantation in a heterotopic rat model.

Current organ preservation strategies subject graft vasculature to severe hypoxia (PO2 approximately 20 Torr), potentially compromising vascular function and limiting successful transplantation. Previous work has shown that cAMP modulates endothelial cell (EC) antithrombogenicity, barrier function,...

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Bibliografiske detaljer

Udgivet i:	J Clin Invest
Principais autores:	Pinsky, D, Oz, M, Liao, H, Morris, S, Brett, J, Sciacca, R, Karakurum, M, Van Lookeren Campagne, M, Platt, J, Nowygrod, R
Format:	Artigo
Sprog:	Inglês
Udgivet:	American Society for Clinical Investigation 1993
Fag:	Research Article
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC288503/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8254053/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI116922
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