Myelin basic protein-specific T lymphocyte repertoire in multiple sclerosis. Complexity of the response and dominance of nested epitopes due to recruitment of multiple T cell clones.

The human T cell response to the myelin basic protein (MBP) has been studied with respect to T cell receptor (TCR) usage, HLA class II restriction elements, and epitope specificity using a total of 215 long-term MBP-specific T cell lines (TCL) isolated from the peripheral blood of 13 patients with m...

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Main Authors: Meinl, E, Weber, F, Drexler, K, Morelle, C, Ott, M, Saruhan-Direskeneli, G, Goebels, N, Ertl, B, Jechart, G, Giegerich, G
Formato: Artigo
Idioma:Inglês
Publicado: 1993
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC288460/
https://ncbi.nlm.nih.gov/pubmed/7504690
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