Contribution of T-Cell Receptor Repertoire Breadth to the Dominance of Epitope-Specific CD8(+) T-Lymphocyte Responses

Dominant epitope-specific CD8(+) T-lymphocyte responses play a central role in controlling viral spread. We explored the basis for the development of this focused immune response in simian immunodeficiency virus (SIV)- and simian-human immunodeficiency virus (SHIV)-infected rhesus monkeys through th...

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Detalhes bibliográficos
Principais autores: Manuel, Edwin R., Charini, William A., Sen, Pritha, Peyerl, Fred W., Kuroda, Marcelo J., Schmitz, Jörn E., Autissier, Patrick, Sheeter, Dennis A., Torbett, Bruce E., Letvin, Norman L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2006
Assuntos:
Pathogenesis and Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1676269/
https://ncbi.nlm.nih.gov/pubmed/17035327
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01479-06
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