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Diverse Cross-Reactive Potential and Vβ Gene Usage of an Epitope-Specific Cytotoxic T-Lymphocyte Population in Monkeys Immunized with Diverse Human Immunodeficiency Virus Type 1 Env Immunogens

An ideal human immunodeficiency virus type 1 (HIV-1) vaccine would elicit potent cellular and humoral immune responses that recognize diverse strains of the virus. In the present study, combined methodologies (flow cytometry, Vβ repertoire analysis, and complementarity-determining region 3 sequencin...

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Detalhes bibliográficos
Main Authors: Hulot, Sandrine L., Seaman, Michael S., Sen, Pritha, Autissier, Patrick A., Manuel, Edwin R., Letvin, Norman L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2748000/
https://ncbi.nlm.nih.gov/pubmed/19640988
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00776-09
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