Similar Epitope Specificities of IgG and IgA Antibodies Elicited by Ad26 Vector Prime, Env Protein Boost Immunizations in Rhesus Monkeys

Vaccine-elicited immunoglobulin G (IgG) has been shown to be important for protection against simian-human immunodeficiency virus (SHIV) infection in rhesus monkeys. However, it remains unclear whether vaccine-elicited IgA responses are beneficial or detrimental for protection. In this study, we eva...

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Vydáno v:J Virol
Hlavní autoři: Kang, Zi Han, Bricault, Christine A., Borducchi, Erica N., Stephenson, Kathryn E., Seaman, Michael S., Pau, Maria, Schuitemaker, Hanneke, van Manen, Danielle, Wegmann, Frank, Barouch, Dan H.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2018
Témata:
Vaccines and Antiviral Agents
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6052297/
https://ncbi.nlm.nih.gov/pubmed/29793950
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00537-18
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