Similar Epitope Specificities of IgG and IgA Antibodies Elicited by Ad26 Vector Prime, Env Protein Boost Immunizations in Rhesus Monkeys

Vaccine-elicited immunoglobulin G (IgG) has been shown to be important for protection against simian-human immunodeficiency virus (SHIV) infection in rhesus monkeys. However, it remains unclear whether vaccine-elicited IgA responses are beneficial or detrimental for protection. In this study, we eva...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Kang, Zi Han, Bricault, Christine A., Borducchi, Erica N., Stephenson, Kathryn E., Seaman, Michael S., Pau, Maria, Schuitemaker, Hanneke, van Manen, Danielle, Wegmann, Frank, Barouch, Dan H.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2018
Assuntos:
Vaccines and Antiviral Agents
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6052297/
https://ncbi.nlm.nih.gov/pubmed/29793950
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00537-18
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