Magnitude and Diversity of Cytotoxic-T-Lymphocyte Responses Elicited by Multiepitope DNA Vaccination in Rhesus Monkeys

In an effort to develop an AIDS vaccine that elicits high-frequency cytotoxic-T-lymphocyte (CTL) responses with specificity for a diversity of viral epitopes, we explored two prototype multiepitope plasmid DNA vaccines in the simian-human immunodeficiency virus/rhesus monkey model to determine their...

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Bibliographic Details
Main Authors: Subbramanian, Ramu A., Kuroda, Marcelo J., Charini, William A., Barouch, Dan H., Costantino, Cristina, Santra, Sampa, Schmitz, Jörn E., Martin, Kristi L., Lifton, Michelle A., Gorgone, Darci A., Shiver, John W., Letvin, Norman L.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2003
Subjects:
Vaccines and Antiviral Agents
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC224609/
https://ncbi.nlm.nih.gov/pubmed/12941922
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.18.10113-10118.2003
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