Magnitude and Diversity of Cytotoxic-T-Lymphocyte Responses Elicited by Multiepitope DNA Vaccination in Rhesus Monkeys

In an effort to develop an AIDS vaccine that elicits high-frequency cytotoxic-T-lymphocyte (CTL) responses with specificity for a diversity of viral epitopes, we explored two prototype multiepitope plasmid DNA vaccines in the simian-human immunodeficiency virus/rhesus monkey model to determine their...

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Bibliographische Detailangaben
Hauptverfasser: Subbramanian, Ramu A., Kuroda, Marcelo J., Charini, William A., Barouch, Dan H., Costantino, Cristina, Santra, Sampa, Schmitz, Jörn E., Martin, Kristi L., Lifton, Michelle A., Gorgone, Darci A., Shiver, John W., Letvin, Norman L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2003
Schlagworte:
Vaccines and Antiviral Agents
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC224609/
https://ncbi.nlm.nih.gov/pubmed/12941922
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.18.10113-10118.2003
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