Myelin autoreactivity in multiple sclerosis: recognition of myelin basic protein in the context of HLA-DR2 products by T lymphocytes of multiple-sclerosis patients and healthy donors.

A panel of 20 human myelin basic protein (hMBP)-specific T-lymphocyte lines was generated from the peripheral blood of eight multiple sclerosis (MS) patients and two healthy donors, most of them expressing the HLA-DR2 haplotype, which is associated with an increased susceptibility to MS. Using HLA-D...

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Autori principali: Pette, M, Fujita, K, Wilkinson, D, Altmann, D M, Trowsdale, J, Giegerich, G, Hinkkanen, A, Epplen, J T, Kappos, L, Wekerle, H
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1990
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC54873/
https://ncbi.nlm.nih.gov/pubmed/1700423
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