Myelin autoreactivity in multiple sclerosis: recognition of myelin basic protein in the context of HLA-DR2 products by T lymphocytes of multiple-sclerosis patients and healthy donors.

A panel of 20 human myelin basic protein (hMBP)-specific T-lymphocyte lines was generated from the peripheral blood of eight multiple sclerosis (MS) patients and two healthy donors, most of them expressing the HLA-DR2 haplotype, which is associated with an increased susceptibility to MS. Using HLA-D...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Pette, M, Fujita, K, Wilkinson, D, Altmann, D M, Trowsdale, J, Giegerich, G, Hinkkanen, A, Epplen, J T, Kappos, L, Wekerle, H
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1990
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC54873/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1700423/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.87.20.7968
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