Increased cyclic guanosine monophosphate production and overexpression of atrial natriuretic peptide A-receptor mRNA in spontaneously hypertensive rats.

Atrial natriuretic peptide (ANP) specifically stimulates particulate guanylate cyclase, and cyclic guanosine monophosphate (cGMP) has been recognized as its second messenger. Spontaneously hypertensive rats (SHR) have elevated plasma ANP levels, but manifest an exaggerated natriuretic and diuretic r...

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Detalhes bibliográficos

Publicado no:	J Clin Invest
Principais autores:	Tremblay, J, Huot, C, Willenbrock, R C, Bayard, F, Gossard, F, Fujio, N, Koch, C, Kuchel, O, Debinski, W, Hamet, P
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Clinical Investigation 1993
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC288435/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7901238/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI116858
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