Increased cyclic guanosine monophosphate production and overexpression of atrial natriuretic peptide A-receptor mRNA in spontaneously hypertensive rats.

Atrial natriuretic peptide (ANP) specifically stimulates particulate guanylate cyclase, and cyclic guanosine monophosphate (cGMP) has been recognized as its second messenger. Spontaneously hypertensive rats (SHR) have elevated plasma ANP levels, but manifest an exaggerated natriuretic and diuretic r...

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Bibliografske podrobnosti

izdano v:	J Clin Invest
Principais autores:	Tremblay, J, Huot, C, Willenbrock, R C, Bayard, F, Gossard, F, Fujio, N, Koch, C, Kuchel, O, Debinski, W, Hamet, P
Format:	Artigo
Jezik:	Inglês
Izdano:	American Society for Clinical Investigation 1993
Teme:	Research Article
Online dostop:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC288435/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7901238/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI116858
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