Thermodynamics of the DNA Structural Selectivity of the Pol I DNA Polymerases from Escherichia coli and Thermus aquaticus

Understanding the thermodynamics of substrate selection by DNA polymerase I is important for characterizing the balance between replication and repair for this enzyme in vivo. Due to their sequence and structural similarities, Klenow and Klentaq, the large fragments of the Pol I DNA polymerases from...

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Main Authors: Wowor, Andy J., Datta, Kausiki, Brown, Hiromi S., Thompson, Gregory S., Ray, Sreerupa, Grove, Anne, LiCata, Vince J.
Format: Artigo
Jezik:Inglês
Izdano: The Biophysical Society 2010
Teme:
Protein
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2884233/
https://ncbi.nlm.nih.gov/pubmed/20550914
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2010.03.021
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