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Role of conserved non-coding DNA elements in the Foxp3 gene in regulatory T-cell fate

Immune homeostasis is dependent on tight control over the size of a population of regulatory T (T(reg)) cells capable of suppressing over-exuberant immune responses. The T(reg) cell subset is comprised of cells that commit to the T(reg) lineage by upregulating the transcription factor Foxp3 either i...

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Bibliografiske detaljer
Main Authors: Zheng, Ye, Josefowicz, Steven, Chaudhry, Ashutosh, Peng, Xiao P., Forbush, Katherine, Rudensky, Alexander Y.
Format: Artigo
Sprog:Inglês
Udgivet: 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2884187/
https://ncbi.nlm.nih.gov/pubmed/20072126
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature08750
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