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Control of regulatory T cell lineage commitment and maintenance

Foxp3-expressing regulatory T (Treg) cells suppress pathology mediated by immune responses against self and foreign antigens, and commensal microorganisms. Sustained expression of the transcription factor Foxp3, a key distinguishing feature of Treg cells, is required for their differentiation and su...

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Bibliographic Details
Published in:Immunity
Main Authors: Josefowicz, Steven Z., Rudensky, Alexander
Format: Artigo
Language:Inglês
Published: 2009
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4410181/
https://ncbi.nlm.nih.gov/pubmed/19464984
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2009.04.009
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