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Control of the inheritance of regulatory T cell identity by a cis element in the Foxp3 locus

In multicellular organisms, specialized functions are delegated to distinct cell types whose identity and functional integrity is maintained upon challenge. However, little is known about the mechanisms enabling lineage inheritance and their biological implications. Regulatory T (Treg) cells, which...

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Detalhes bibliográficos
Main Authors: Feng, Yongqiang, Arvey, Aaron, Chinen, Takatoshi, van der Veeken, Joris, Gasteiger, Georg, Rudensky, Alexander Y
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4151558/
https://ncbi.nlm.nih.gov/pubmed/25126783
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2014.07.031
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