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Activated protein C cofactor function of protein S: a critical role for Asp95 in the EGF1-like domain
Protein S has an established role in the protein C anticoagulant pathway, where it enhances the factor Va (FVa) and factor VIIIa (FVIIIa) inactivating property of activated protein C (APC). Despite its physiological role and clinical importance, the molecular basis of its action is not fully underst...
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| Autors principals: | , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society of Hematology
2010
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2884152/ https://ncbi.nlm.nih.gov/pubmed/20308596 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2009-11-256610 |
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