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Decitabine maintains hematopoietic precursor self-renewal by preventing repression of stem cell genes by a differentiation inducing stimulus
The cytosine analogue decitabine alters hematopoietic differentiation. For example, decitabine treatment increases self-renewal of normal hematopoietic stem cells. The mechanisms underlying decitabine induced shifts in differentiation are poorly understood, but likely relate to the ability of decita...
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2884053/ https://ncbi.nlm.nih.gov/pubmed/20501800 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-10-0191 |
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