p53 independent epigenetic-differentiation treatment in xenotransplant models of acute myeloid leukemia

Suppression of apoptosis by TP53 mutation contributes to resistance of acute myeloid leukemia (AML) to conventional cytotoxic treatment. Using differentiation to induce irreversible cell cycle exit in AML cells could be a p53-independent treatment alternative, however, this possibility requires eval...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Ng, Kwok Peng, Ebrahem, Quteba, Negrotto, Soledad, Mahfouz, Reda Z., Link, Kevin A., Hu, Zhenbo, Gu, Xiaorong, Advani, Anjali, Kalaycio, Matt, Sobecks, Ronald, Sekeres, Mikkael, Copelan, Edward, Radivoyevitch, Tomas, Maciejewski, Jaroslaw, Mulloy, James C., Saunthararajah, Yogen
Format: Artigo
Sprog:Inglês
Udgivet: 2011
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3668642/
https://ncbi.nlm.nih.gov/pubmed/21701495
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/leu.2011.159
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker