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Spindly/CCDC99 Is Required for Efficient Chromosome Congression and Mitotic Checkpoint Regulation
Spindly recruits a fraction of cytoplasmic dynein to kinetochores for poleward movement of chromosomes and control of mitotic checkpoint signaling. Here we show that human Spindly is a cell cycle–regulated mitotic phosphoprotein that interacts with the Rod/ZW10/Zwilch (RZZ) complex. The kinetochore...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The American Society for Cell Biology
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2883941/ https://ncbi.nlm.nih.gov/pubmed/20427577 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E09-04-0356 |
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