Human chromokinesins promote chromosome congression and spindle microtubule dynamics during mitosis

Chromokinesins are microtubule plus end–directed motor proteins that bind to chromosome arms. In Xenopus egg cell-free extracts, Xkid and Xklp1 are essential for bipolar spindle formation but the functions of the human homologues, hKID (KIF22) and KIF4A, are poorly understood. By using RNAi-mediated...

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Detalhes bibliográficos
Main Authors: Wandke, Cornelia, Barisic, Marin, Sigl, Reinhard, Rauch, Veronika, Wolf, Frank, Amaro, Ana C., Tan, Chia H., Pereira, Antonio J., Kutay, Ulrike, Maiato, Helder, Meraldi, Patrick, Geley, Stephan
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2012
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Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3432768/
https://ncbi.nlm.nih.gov/pubmed/22945934
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201110060
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